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Aloe Vera UK

Aloe Vera UK is a natural product that is used in cosmetology. Although there are many indications for its usage, controlled trials are necessary to verify its effectiveness. This article briefly reviews the aloe vera plant’s properties, mechanism of action, and clinical uses.

Aloe Vera UK has been used for centuries to promote beauty, health, and skin care. Aloe vera is derived from the Arabic word Aloeh, which means “shining bitter substance” and “vera,” in Latin “true”. 2000 years ago, Greek scientists considered Aloe aloe vera ukera UK to be the universal panacea. Aloe vera was called “the plant that gives immortality” by the Egyptians. It is still used in dermatology for many purposes.

Histories

For millennia, Aloe Vera UK was used in many cultures: Egypt, India and Mexico. Egyptian queens Nefertiti, Cleopatra and Cleopatra also used it as part their beauty regimens. Alexander the Great and Christopher Columbus used it for wound treatment. Aloe vera was first mentioned in English by John Goodyew, in A.D 1655 of Dioscorides Medical Treatise De Materia Medica.

Plant

Aloe Vera UK’s botanical name is Aloe barbadensis miler. It is a perennial, xerophytic and succulent shrubby or arborescent plant that belongs to the Asphodelaceae family (Liliaceae). It is found in dry areas of Africa, Asia and Europe, as well as America. It is found in India’s Rajasthan, Andhra Pradesh and Gujarat, Maharashtra, Maharashtra, Tamil Nadu, and Maharashtra.

Anatomy

Triangular, fleshy, triangular leaves are found on this plant. They also have yellow tubular flowers, many seeds, and serrated edges. The inner layer of each leaf is made up of three layers. 2) The bitter yellow sap layer, which is the middle layer of latex. It contains anthraquinones as well as glycosides. The outer layer of 15-20 cells, known as the rind. It has protective functions and synthesizes proteins and carbohydrates. The vascular bundles that transport substances like water (xylem), starch (phloem), and other compounds are found within the rind.

Active components that are related to its properties: Aloe Vera UK contains 75 potential active constituents: vitamins and enzymes, minerals.

  1. Vitamins It has vitamins A (betacarotene), E and C, which are all antioxidants. It also contains vitamin B12 and folic acid. Antioxidant neutralizes the free radicals.

  2. Enzymes: This enzyme contains 8 enzymes. They are: amylase (alkaline phosphatase), bradykinase (5-hydroxypeptidase), catalase, cellulase and lipase), bradykinase (6-hydroxypeptidase), carboxypeptidase (7-carboxypeptidase), catalase, lipase and lipase), peroxidase) When applied topically to the skin, Bradykinase reduces inflammation. Other enzymes aid in the reduction of sugars or fats.

  3. Minerals It contains calcium, chromium and copper as well as manganese (potassium), potassium, sodium, and zinc. They are vital for proper functioning of different enzyme systems in different metabolic pathways. Very few antioxidants are available.

  4. Sugars: It provides monosaccharides (glucose and fructose) and polysaccharides: (glucomannans/polymannose). These polysaccharides are made from the plant’s mucilage layer and are called mucopolysaccharides. The most prominent monosaccharide is mannose-6-phosphate, and the most common polysaccharides are called glucomannans [beta-(1,4)-acetylated mannan]. Acemannan, a well-known glucomannan, has also been discovered. A prominent glucomannan, Acemannan, was also discovered.

  5. Anthraquinones It contains 12 anthraquinones which are phenolic compounds that were traditionally used as laxatives. Emodin, emodin, and aloin are analgesics.

  6. Fatty Acids: This provides 4 plant steroids, cholesterol, campesterol and b-sisosterol. These have an anti-inflammatory effect and lupeol has antiseptic and analgesic qualities.

  7. Hormones : Auxins, gibberellins, that aid in wound healing and have an anti-inflammatory effect.

  8. Other: It contains 20 of the 22 essential amino acids that are humanly required and 7 of the eight essential amino acids. It also contains salicylic acids, which have anti-inflammatory and antibacterial qualities. Lignin, a non-toxic substance, is added to topical preparations to enhance the penetration of other ingredients into the skin. The gel’s 3% contains saponins, which are soapy substances. They have antiseptic and cleansing properties.

Mechanism of actions

  1. Healing properties 11

  2. The effects of UV and gamma radiation on the skin: It reduces the production and release of skin keratinocyte-derived immunosuppressive cytokines such as interleukin-10 (IL-10) and thus prevents UV-induced suppression of delayed type hypersensitivity. It decreases the production and availability of skin keratinocyte derived immunosuppressive cytokines like interleukin-10 (IL-10), and prevents UV-induced suppression.

  3. Anti-inflammatory activity: The cyclooxygenase pathway is inhibited by Aloe Vera UK and prostaglandin E2 is reduced from arachidonic acids. C-glucosyl-chromone, a novel anti-inflammatory compound, was recently isolated from gel extracts.

  4. Effects on the immune system: Alprogen inhibit calcium influx into mast cells, thereby inhibiting the antigen-antibody-mediated release of histamine and leukotriene from mast cells.7 In a study on mice that had previously been implanted with murine sarcoma cells, acemannan stimulates the synthesis and release of interleukin-1 (IL-1) and tumor necrosis factor from macrophages in mice, which in turn initiated an immune attack that resulted in necrosis and regression of the cancerous cells.15 Several low-molecular-weight compounds are also capable of inhibiting the release of reactive oxygen free radicals from activated human neutrophils.16

  5. The laxative effects of Latex contains anthraquinones, which are potent laxatives. It stimulates intestinal peristalsis, increases intestinal water content and stimulates mucus production.

  6. Antiviral activity and antitumor activity These actions can be caused by either indirect or direct effects. Direct effects are due to the stimulation of the immune systems, while indirect effect is due anthraquinones. Anthraquinones have an indirect effect on the immune system, while direct effects are due to benzopyrene-DNA-adduct formation. An induction of glutathione S-transferase and an inhibition of the tumor-promoting effects of phorbol myristic acetate has also been reported which suggest a possible benefit of using aloe gel in cancer chemoprevention.19,20

  7. Moisturizing effect and anti-aging: Mocopolysaccharides aid in bringing moisture to the skin. Aloe stimulates the fibroblast, which makes collagen and elastin fibers. This makes the skin elastic and less wrinkled. Aloe also acts as a glue to the superficial flaking epidermal cell layers, which binds them together and softens the skin. Zinc acts as an astringent and tightens pores, while the amino acids soften hardened skin cells. Aloe Vera UK gel has been shown to moisturize dry skin due to occupational exposure.

  8. Antiseptic Effect: The antiseptic properties of Aloe Vera UK include 6 agents: Lupeol (salicylic acid), urea nitrogen and cinnamonic acid, as well as phenols, sulfur, and urea nitrogen. All of them have anti-fungal properties against bacteria, viruses and fungi.

Aloe Vera UK clinical uses: Most of the evidence supporting aloe vera’s clinical use in medicine is anecdotal. Although many of these uses seem interesting, controlled trials are necessary to confirm its effectiveness in the following diseases. 22 ,

A. A. Safety and effectiveness are not always proven.

Conditions: Seborrheic Dermatitis,24 Psoriasis Vertilis,25,26 Genital Herpes,27.28 Skin Burns,5,29 Diabetes (Type 2),32,33 Ulcerative Colitis34 Wound Healing (Results from aloe on wound heal are mixed with some studies reporting positive results35,36,38,37 and others reporting no benefit36,38,36,38,37,38,36,37,38,38,36,41 lichen planus 42 frostbite,42 frostbite43,43 Aphthous Stomatitis,43 and 44 and44.

B. B. These products are not always safe or effective and have not been tested on humans.

Conditions: Alopecia.

Side effects

Topical It can cause redness, burning sensations, and occasionally generalized dermatitis. Anthraquinones such as barbaloin or aloin are most commonly responsible for allergic reactions. To test for allergic reactions, it is best to first apply the product to a small area.

Oral Red urine, stomach cramps, diarrhea and hepatitis. Long-term use is linked to an increase in the risk of developing colorectal carcinoma. Electrolyte imbalances may result from laxative effects (low potassium levels).

Contraindication: Not recommended in cases of allergy to Liliaceae plants.

Pregnancy & Breastfeeding: Oral Aloe is not recommended during pregnancy. It theoretically stimulates uterine contractions. In breastfeeding mothers it can sometimes cause gastrointestinal distress in their infant.

Interactions The application of aloe vera UK gel to the skin can increase the absorption rate of steroid creams like hydrocortisone. Due to its potassium lowering effects, it can reduce the effectiveness of digoxin or digitoxin and increase their adverse effects. Furosemide and Aloe vera may increase the likelihood of potassium depletion. It can lower blood sugar levels, which may cause interactions with insulin and oral hypoglycemic medications.

Aloe vera is a versatile plant with many properties and uses. However, some could be mythical and others could be true magic. Future controlled studies will be required to verify the effectiveness of Aloe Vera under different conditions.

Aloe Vera UK